The gut-brain axis and the psychobiome

Brain health and function is linked to the composition of the microbial eco-system of the gut. These microbes influence thoughts, feelings and behaviour and regulate the gut-brain axis. This two-way communication network between the gut’s microbial eco-system – otherwise known as the psychobiome – and the central nervous system plays a role in cognitive function (learning, memory, focus), digestive health and mood.

One of the key factors in supporting the health and vigour of the gut-brain axis is to maintain a diverse and balanced psychobiome. Psychobiotics are commensal probiotic bacteria that make up the psychobiome and support positive changes in brain function. Gut Feelings™ contains the most widely researched psychobiotic available, Bifidobacterium longum 1714™, that supports feelings of calm, relaxation and balance during times of stress, low energy, mood changes and sleep challenges.

Why these ingredients?

Bifidobacterium longum 1714™

This next-generation psychobiotic helps the gut and brain stay in sync when life gets stressful. Studied to support the HPA stress axis, it helps keep cortisol in a healthy range and supports clear thinking under pressure. Research also shows benefits for memory, calm mood, and overall mental resilience, making 1714™ a true gut-brain ally for everyday stress and focus.

Saffron stigma extract (Crocus sativus L)  

Celebrated as one of nature’s most precious botanicals, saffron stands out for emotional balance. Backed by research, this botanical is prized for its ability to support positive mood and nervous tension. Compounds in saffron have been shown to influence key neurotransmitters, including serotonin and dopamine, which are involved in maintaining a brighter outlook and steady mental energy during everyday stress.

Vitamins B6 & B12

These nervous-system heroes act as essential cofactors in the creation of serotonin, dopamine and GABA, key neurotransmitters that drive calm mood, sharp focus, and balanced stress response. By fuelling red-blood-cell formation, supporting methylation, and converting food into steady cellular energy, these B's help keep nerves firing smoothly and mental clarity strong through everyday pressures.


The science behind 1714™ strain

Gutsi®’s Gut Feelings™ features Bifidobacterium longum 1714™, a unique probiotic that nourishes the “psychobiome” – the gut microbes linked with gut-brain communication. This patented strain is studied for its role in supporting the natural connection between digestive and mental well-being. B. longum 1714™ has been researched for its influence on the body’s stress-response pathways, including the HPA axis, and on key brain messengers such as serotonin and GABA. These actions help maintain balanced gut-brain dialogue and everyday mental clarity, supporting a sense of calm and steady focus.


The Gut Feelings™ difference

Formulator Kiran Krishnan is a research Microbiologist with over 20 years' experience and a leader in microbiome and probiotic research.

Gut Feelings™ recognises the vital importance the gut plays in mental and emotional wellbeing, harnessing the power of the gut-brain axis to unlock your inner calm

Psychobiotics are specific probiotic bacteria that supports brain health and function through the gut-brain axis.

Gut Feelings™ novel formulation uses cutting-edge probiotic technology with the unique, patented and most widely-researched psychobiotic strain of Bifidobacterium longum – B. longum 1714™.

Mood-brightening saffron and energy-supportive B-vitamins provide a natural lift while helping the nervous system adapt to life’s daily stressors, supporting mental clarity, balanced mood, and sustained vitality.

Gutsi® Gut Feelings™ contains cellulose from acacia wood fibre that acts as a prebiotic for gut bacteria. The psychobiotic and cellulose are encapsulated in a vegetarian capsule made of cellulose from pine trees and water.




Take control of your health and feel the Gutsi® difference.